PuRe™ Pupillometer — Free From Ambient Light Influence

Superior accuracy. No disposables. Instant EMR upload.

our SOLUTION

Introducting PuRe™ Pupillometer

Solvemed's smartphone-based FDA medical device enables accurate and reliable pupil size and reactivity testing without the need for any hardware.

Accessible

No more looking for a pupillometer around the unit — it's with you when you need it.

Free from disposables

No more "smart" plastic eye cups. Save time, money, and the environment.

Lighting-invariant

Accurate pupil testing in any ambient light conditions.

EMR-integrated

Integrates with your hospital's EMR system (optional).

LeGACY tools

Pupil reactivity testing
needs a revolution.

Medical penlight

Penlight exam represents a subjective pupillary assessment often resulting in measurement errors.

Subjective

Unreliable, high inter-practitioner variability

Variable

Variable light pulse intensity

Not durable

Fragile and easily misplaced

No data recording

Analog tool

No EMR integration

Requires manual typing of results into the EMR

Conventional pupillometer

Infrared pupillometry improves objectivity, however it requires expensive, cumbersome, and fragile hardware.

Affected by ambient light

Prone to inaccuracy due to effects of ambient light

Limited EMR integration

Does not effectively connect to hospital EMR systems

Expensive

High upfront capital spend, recurrent disposables costs

Cumbersome

Requires wired connection, frequent charging, and repairs

Environmentally unsustainable

Requires extra hardware device and plastic disposables

PROBLEM

Ambient light impairs conventional pupillometry

Neurological exams rely on pupillary assessment. Yet, pupil testing tends to be either subjective and thus prone to inaccuracies or performed with expensive and cumbersome conventional infrared pupillometers, whose accuracy can be significantly impaired by ambient light.*

>0.7

Conventional pupil reactivity index dropped 0.7 or more in one-fourth of left eyes in dark vs. bright conditions.¹

6/8

of pupillometry parameters changed directly due to the ambient light change¹, with 7/8 reported previously.²

25%

of patients showed a difference of 0.6 or more in reported pupil reactivity in dark vs. bright conditions.¹

>0.7

Conventional pupil reactivity index grew 0.7 or more in 25% of left eyes after a switch from bright to dark conditions.¹

*All the results are statistically significant and have been obtained in neuro-intensive care patients.

¹ Holmskär S, et al. J Clin Monit Comput. 2025

Read more

² Ong C, et al. Neurocrit Care. 2018

Read more

Changes in the pupil reactivity level of 0.6 or more can well be misinterpreted as a deterioration or improvement of neurological status, particularly in patients hovering around the 3.0 cut-off level.¹

CLINICAL EVIDENCE

PuRe™ Pupillometer — reliable in any ambient light

PuRe™ Pupillometer shows superior clinical performance across various levels of ambient light compared to conventional pupillometers.

The PuRe™ score is the only pupil reactivity score unaffected by ambient light.

CLINICAL RESEARCH

Making the Pupil Reactivity (PuRe™) score immune to lighting changes

Solvemed’s computational pupillometry represents a novel method to effectively mitigate the confounding effects of ambient light. Exposure level and initial pupil size are used to compute lighting-corrected parameters, with are then combined to optimize discrimination between reactive and unreactive pupils, resulting in the PuRe score.

The formulae behind the score are openly available for the benefit of the clinical research community.

Read more

Lighting-Invariant Open-Source PuRe™ score.

Our clinical research collaborations
EMR INTEGRATION

Effective integration with your EMR system

We leverage industry-leading connectivity and security measures to let you focus on the patient.

CONNECTIVITY

Secure and seamless EMR integration

Effective Electronic Medical Record (EMR) integration lets health care teams focus on the patient. To that end, PuRe Pupillometer supports effecrtive integration with all major hospital EMRs using latest data encryption and connectivity industry standards.

The system represents a convergence of advanced software and robust data security mechanisms. It harnesses the inherent security features of Apple's iOS, including Face ID and HIPAA-compliant web services to ensure secure authentication of users and data transfers.

Read more

PuRe™ Pupillometer Connectivity Framework.

EMR SYSTEMS we integrate with
compliance

Secure by design. Privacy prioritized.

Solvemed’s PuRe™ Pupillometer has been designed with IT security and patient privacy in mind. We employ the latest encryption standards for maximum compliance.

PuRePupillometer Mobile App

  • Regulated FDA Class I medical device
  • Software as Medical Device (SaMD) product category

Solvemed
Connect

  • Full integration with your EMR system within <12 weeks (optional)
  • Industry-standard cryptographic algorithms and protocols

Secure
Cloud

  • SOC2- and HIPAA-compliant
  • Secure data processing
  • Data encrypted in transit and at rest
TESTIMONIALS

What experts say

We work closely with clinicians to develop game-changing tools that reshape clinical practice and research.

Dr. Simon Raby, M.D.

Neuro-intensivist, Clinical Director at Oxford Major Trauma Centre

Neurocritical Care

With accurate, repeatable assessment of pupil size, this application could improve diagnosis of life-threatening complications of traumatic brain injury. This could reduce time to surgery.

Dr. David Li, M.D.

Intensivist

Critical Care

Solvemed's PuRe Pupillometer makes a key part of the neurological exam standardized and reproducible, just like the automated cuff did for blood pressures. That's why it can and should be in every clinician's pocket.

Dr. Edward Yap, M.D.

Anesthesiologist, Assistant Chief of Anesthesia

Critical Care

The examination of pupils is a standard in my neurological assessment during perioperative care. Solvemed's PuRe Pupillometer is accurate and easily accessible, making it my an indispensable tool.

Dr. Nicholas Mark, M.D.

Intensivist

Critical Care

I routinely use the Solvemed's PuRe Pupillometer when taking care of critically ill people in the medical, surgical and cardiac ICU. It's accurate, easy to use, and always available, because it's an app on my phone. I also appreciate the transparency of having an open source Pupil Reactivity (PuRe) score.

Designed for
  • neuro-ICUs


  • medical-ICUs

  • cardiac-ICUs

  • surgical-ICUs

  • trauma centers

  • stroke units

  • emergency rooms

  • nursing staff

  • physicians

  • researchers

looking for reliable pupil testing.