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February 4, 2025

Solvemed Showcases PuRe™ Pupillometer at International Stroke Conference (ISC) 2025

Solvemed demonstrates AI-driven smartphone-based pupillometry technology for improved stroke care at ISC 2025.

Dr Michal Wlodarski
Chief Operating Officer, Co-founder

Showcasing AI-Driven Pupillometry at ISC 2025

Solvemed participated at the International Stroke Conference (ISC) 2025, one of the world's leading gatherings for stroke care professionals and researchers. Our team demonstrated the capabilities of our AI-driven neurodiagnostic device, PuRe™ Pupillometer, positioning smartphone-based pupillometry as a tool for improving acute stroke management in critical care environments. The quantitative pupillometry solution generated interest among nurses, intensivists, and healthcare providers who recognized its potential to enhance stroke patient care through objective neurodiagnostic assessments.

AI-Driven Quantitative Pupillometry with PuRe™ Pupillometer

The PuRe™ Pupillometer represents an approach to neurodiagnostics, employing AI-driven algorithms to deliver precise quantitative pupillometry assessments of the Pupillary Light Reflex. This smartphone-based pupillometry device utilizes artificial intelligence and high-resolution imaging to capture and analyze pupillary responses with submillimeter accuracy and millisecond timing precision. The AI-driven technology addresses the subjectivity and inter-observer variability that have historically limited manual pupil assessments in critical care settings, providing stroke care teams with standardized neurodiagnostic data for clinical decision-making.

Value of Quantitative Pupillometry in Stroke Care

Objective pupillometry provides valuable insights in stroke care by enabling precise and standardized assessments of the Pupillary Light Reflex, which correlates significantly with intracranial midline shift and neurological deterioration. Osman et al. (2019) demonstrated that objective pupillometry metrics, including Pupillary Light Reflex and constriction velocity, have a meaningful correlation with the degree of horizontal intracranial midline shift in patients with acute ischemic or hemorrhagic stroke. Importantly, this correlation did not extend to pupil size alone, emphasizing the significance of pupillary reactivity rather than absolute pupil dimensions. Similarly, Giamarino et al. (2021) reinforced these findings, noting significant correlations between the Pupillary Light Reflex, anisocoria, and midline shift measured at both the septum pellucidum and pineal gland. Furthermore, Zanier et al. (2024) highlight the broader relevance of continuous neuromonitoring methods, including pupillometry, in enhancing personalized management and prognostication in acute brain injuries. Together, these correlations highlight pupillometry's capacity to identify early and subtle neurological changes, which can precede clinical deterioration, thereby facilitating timely interventions and potentially improving patient outcomes.

Looking Forward: The Future of AI-Driven Neurodiagnostics in Critical Care

Solvemed's participation at ISC 2025 reinforced the growing recognition of smartphone-based pupillometry as an essential tool for modern stroke care. The positive reception of PuRe™ Pupillometer among critical care professionals demonstrates the healthcare community's readiness to embrace AI-driven neurodiagnostic solutions that can improve patient outcomes through objective, standardized assessments. Our team also presented scientific posters at ISC 2025 detailing clinical outcomes and research findings from quantitative pupillometry applications in stroke care. For comprehensive details regarding these research presentations, please refer to our dedicated article covering the scientific posters showcased at the conference.

Dr Michal Wlodarski
Chief Operating Officer, Co-founder
Sources:

References:

Osman, M., Stutzman, S.E., Atem, F., et al. (2019). Correlation of Objective Pupillometry to Midline Shift in Acute Stroke Patients. Journal of Stroke and Cerebrovascular Diseases.

Robba, C., Zanier, E.R., Soto, C.L., et al. (2024). Mastering the brain in critical conditions: an update. Intensive Care Medicine Experimental.

Giamarino, K., Blessing, R., Boelter, C., et al. (2021). Exploring the Relationship Between Objective Pupillometry Metrics and Midline Shift. Journal of Neuroscience Nursing.